Mahamanjishthadya Rishta is a preparation of Ayurveda which is effective in treating a number of skin related disorders. This Ayurvedic medicine consists of precious Ayurvedic herbs like Manjistha, Vidanga, Neem Twak, Rakta Chandana, Musta, Kutaj, Sariva, Bharangi, and Triphala. This Ayurvedic medicine possesses powerful antipruritic agents that help to alleviate the itchiness and pruritus. Leprosy is a common health disorder where infectious skin infection manifests that may cause skin lesion and nerve damage. Mahamanjishthadya Rishta is capable of healing Leprosy and that too with effectively. Syphilis is another skin ailment where the patient has to go through various complications. Mahamanjishthadya Rishta is also found to be enormously beneficial in treating Syphilis too. This Ayurvedic medicine is believed to have acne healing agents that treat acne like a pro. It works by purifying the blood and improving the circulation of the blood in the dermal layer. Elephantiasis can be also effectively managed with the efficacy of Mahamanjishthadya Rishta. Taking the right dose of this Ayurvedic medicine is highly imperative else it has to offer some adverse effects. Prescription of the registered doctor is highly recommended.